As we age and live active lives, many people experience joint pain, inflammation, fractures, ligament damage and aging of the skin. The body attempts to heal itself by producing different types of proteins and sending them to the affected area.
In some cases, the body’s natural response might not be enough to resolve your symptoms. Chronic pain, inflammation or soreness may benefit from the use of human exosome therapy. Exosomes are also quite beneficial for skin rejuvenation and brightening.
What are Exosomes?
Exosomes are extracellular vesicle (EV’s). They consist of enclosed proteins and micro-RNA which are produced by the endosomes (membrane-bound compartments within the cell) These endosomes are released from the inside of the cell to outside the cell.
The exosome external membranes are made up of a bit of the cell’s plasma membrane. Exosomes can be found in different tissues throughout the body. They are also present in blood, cerebrospinal fluid and urine.
What do Exosomes do?
Exosomes function by communicating with other body cells. They can travel throughout the body and deliver a message from one cell to another. They can even merge with a new cell in order to deliver information. Exosomes are thought to affect the immune system’s response to infections and tumors.
They may also carry cargo and deliver it to cells. Scientists have found exosomes carrying cytokines and lipopolysaccharides. Cytokines are cellular growth factors, important in cell signaling. Lipopolysaccharides trigger an immune response from the body.
How Exosomes Are Used in Regenerative Medicine
In regenerative medicine, exosomes can be used to stimulate tissue growth, repair, and regeneration. The exosomes do this in several ways. One way is via delivery of molecular structures to a targeted area of the body. Those molecular structures can be used by the body to repair damage in a ligament, cartilage or bone. The presence of exosomes triggers growth factors to be released from muscle and bone cells.
This hastens the repair process when a bone is fractured or a ligament or muscle is torn. They also trigger the repair of soft tissues for faster wound healing after an injury to the skin. The exosomes are able to target areas that are inflamed, and they find the site of the problem and start working in a short amount of time.
References:
- https://regenomedix.com/wp-content/uploads/Exosomes-to-Treat-Joint-Injury-and-Osteoarthritis-Feb-2019.pdf
- https://regenomedix.com/wp-content/uploads/Exosomes-in-Skin-Repair-Dec-2018.pdf
- https://regenomedix.com/wp-content/uploads/Exosomes-in-Wound-Healing-May-2017.pdf
- https://regenomedix.com/wp-content/uploads/Exosomes-and-their-Role-in-Regenerative-Medicine-Nov.-2018.pdf
- https://regenomedix.com/wp-content/uploads/Role-of-Exosomes-in-Joint-Disease-May-2018.pdf
- https://regenomedix.com/wp-content/uploads/Exosomes-What-Are-They-Exactly-June-2016.pdf
- https://regenomedix.com/wp-content/uploads/Exosomes-to-Treat-Joint-Injury-and-Osteoarthritis-Feb-2019.pdf